a facile synthesis of (s) – (-) – propranolol
نویسندگان
چکیده
a one-pot synthesis of (s)-(-)-propranolol is reported. zn(no3)2/(+)-tartaric acid catalyzed enantioselective synthesis of (s)-(-)-propranolol via kinetic resolution of key intermediate ?-naphthyl glycidyl ether with high optical and chemical yield.
منابع مشابه
A FACILE SYNTHESIS OF (S) – (-) – PROPRANOLOL
A one-pot synthesis of (S)-(-)-propranolol is reported. Zn(NO3)2/(+)-tartaric acid catalyzed enantioselective synthesis of (S)-(-)-propranolol via kinetic resolution of key intermediate ?-naphthyl glycidyl ether with high optical and chemical yield.
متن کاملA facile and efficient synthesis of Baclofen
γ-Aminobutiric acid (GABA), the major inhibitory neurotransmitter in the central nervous system is activated by the antispastic and muscle relaxant agent, Baclofen, which is a lipophilic derivative of GABA. Because of its biological and pharmacological importance, there are several reports in the literature about the synthesis of baclofen since 1962. In this study baclofen was easily synthesize...
متن کاملFacile one-pot synthesis of S-alkyl thiocarbamates.
We report a novel one-pot two-step synthesis of a variety of S-alkyl thiocarbamates. This method offers a two-directional approach making use of trichloroacetyl chloride, requires no complex starting material, incorporates a variety of substituents, and proceeds in high yields.
متن کاملA Facile Solvothermal Method for Synthesis of CuInS2 Nanostructures
CuInS2 nanostructures were synthesized via a simple surfactant-free solvothermal route. In this synthesis, thiosemicarbazide and thioglycolic acid were used as sulfur sources. The effects of different parameters such as type of precursor and time on the morphology and particle size of the samples have been investigated. The nanostructures were characterized by means ...
متن کاملa facile and efficient synthesis of baclofen
γ-aminobutiric acid (gaba), the major inhibitory neurotransmitter in the central nervous system is activated by the antispastic and muscle relaxant agent, baclofen, which is a lipophilic derivative of gaba. because of its biological and pharmacological importance, there are several reports in the literature about the synthesis of baclofen since 1962. in this study baclofen was easily synthesize...
متن کاملFacile synthesis of AsP3.
The elements phosphorus and arsenic form tetrahedral P4 and As4 molecules, of which the former is a commodity chemical and the latter unstable. Previously, information on molecules of intermediate composition was limited to a spectroscopic study involving hot gas-phase mixtures of phosphorus and arsenic. The AsP3 molecule has yielded to chemical synthesis and was isolated in solid form as a pur...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
journal of sciences islamic republic of iranجلد ۱۴، شماره ۱، صفحات ۰-۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023